A synthetic peptide elicits antibody reactive with the native duck hepatitis B virus pre-S protein.

نویسندگان

  • Y M Wen
  • Y Y Xu
  • W Zhang
  • Y Z Liu
چکیده

Synthetic peptides P37-49 and P63-79, derived from the pre-S region of duck hepatitis B virus (DHBV), have been synthesized. Only P37-49 was reactive with rabbit anti-DHBs/pre-S antibodies by radioimmunoprecipitation. Antiserum prepared against P37-47 reacted with a 35K polypeptide of native DHBs/pre-S by immunoblotting. It is concluded that P37-49 (MGQHPAKSMDVRR) mimics one of the epitopes of the DHBV pre-S antigen.

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عنوان ژورنال:
  • The Journal of general virology

دوره 71 ( Pt 10)  شماره 

صفحات  -

تاریخ انتشار 1990